P. Krastev, and B. Tracey
Neurometrix, Inc., Waltham, Massachusetts, USA
Nerve localization is important for applications in regional anesthesia. Localization is achieved by stimulating the nerve with an electric field produced by a current from a needle inserted into the body of the patient, close to the target nerve. Modeling of the electric field in close proximity to the nerve may help to explain observed variations in threshold currents and can help to ...
Interfacing Continuum and Discrete Methods: Convective Diffusion of Microparticles and Chemical Species in Microsystems
CEA-LETI, Department of Biotechnology, Grenoble, France
Convective transport of macromolecules or micro and nanoparticles in microsystems are usually predicted by solving the Navier Stokes equations for the carrier fluid and a concentration equation for the diffusing species. In the case of isolated particles or complicated geometries with extremely small apertures or microporous material, the concentration equation maybe replaced by a Monte Carlo ...
M. Suárez , and F. Samaniego 
Faculty of Sciences, Michoacán University (UMSNH), Morelia, Michoacan, Mexico
Faculty of Engineering Postgrade Studies Division, National University of Mexico (UNAM), Mexico City, Mexico
New geothermal energy sources hold promise for the future. Deep submarine geothermal energy related to hydrothermal vents is emerging in many places along the oceanic spreading centers. Shallow submarine geothermal systems are found near to continental platforms. We present the initial development of mathematical models to simulate the energy transport in submarine systems. A model for the ...
M. Blaziková, J. Malínský, D. Stanek, and P. Herman
Faculty of Mathematics and Physics, Charles University, Prague, Czech Republic
Institute of Experimental Medicine, Prague, Czech Republic
Institute of Molecular Genetics, Prague, Czech Republic
Small nuclear ribonucleoprotein particles (snRNPs) are essential supramolecular complexes involved in pre-mRNA splicing, the process of post-transcriptional RNA modifications. The particles undergo complex assembly steps inside the cell nucleus in a highly dynamic compartment called the Cajal body. We have previously shown that the free diffusion model does not fully describe the snRNP motion ...
G. Long, D. Plescia, and P. Shires
Ethicon Endo-Surgery, Cincinnati, OH, USA
Thermal ablation of malignant tumors has been conducted in patients who are not candidates for surgery for more than ten years. Recently it has been shown that low energy DC pulses can cause cell necrosis. An undesirable characteristic of DC pulses in-vivo is the stimulation of skeletal muscle. The intensity of the contraction depends in part on the duration and height of the pulse. Through the ...
A. Mohammed, and A. Jeremic
McMaster University, Hamilton, L8S4K1, Canada
Signal processing algorithms for chemical sensing/monitoring have been subject of considerable research interest in the recent years mainly due to their diverse applicability. When the concentration of chemical agent is small, the dispersion of particles is governed by stochastic differential equations describing more complex motion mechanisms such as Brownian motion. In this paper we propose ...
T. Reissman, and E. Garcia
Sibley School of Mechanical and Aerospace Engineering, Cornell University, Ithaca, NY, USA
In this work, an analysis is presented for a 3-dimensional RF MEMS coil using the COMSOL AC/DC module in conjunction with the CAD import module. The realization of being able to produce such 3-dimensional RF coils allows for less surface area to be needed for similar inductor performance in comparison to larger planar RF coils by maintaining the same number of turns through super-positioning of ...
R. Sadleir, A. Minhas, and E.J. Woo
University of Florida, Gainesville, FL, USA
Kyung Hee University, Seoul, Republic of Korea
In an earlier work we developed a finite element bidomain model of an aplysia abdominal ganglion in order to estimate the sensitivity of this contrast mechanism to changes in cell membrane conductance occurring during a gill-withdrawal reflex. We used our model to determine both current density and magnetic potential distributions within a sample chamber containing an isolated ganglion when it ...
Pryor Knowledge Systems, Inc., Bloomfield Hills, MI, USA
The concept of virtual prototyping can be found linked to many different keywords in the literature: modeling, look-ahead problem solving, etc. This poster paper briefly discusses the potential real benefits that can be realized through pre-build cost savings, minimization of the number of prototype builds, and post-build problem avoidance for physical prototypes and production products. ...
S. Maloney[1,2], Y. Li[1,2], G. Auner, and J. Smolinski
Wayne State University, Detroit, MI, USA
Lawrence Technological University, Southfield, MI, USA
We are working on a microfabricated lysing chip that uses a piezoelectric actuator to provide ultrasonic energy to break apart cells. The device contains pillars with varying dimensions. We hypothesize that increasing the aspect ratio of pillars will increase the efficiency of the transfer of ultrasonic energy into the fluid phase and enhance the lysing efficiency. The fluid structure ...