S. Maloney[1,2], Y. Li[1,2], G. Auner, and J. Smolinski
Wayne State University, Detroit, MI, USA
Lawrence Technological University, Southfield, MI, USA
We are working on a microfabricated lysing chip that uses a piezoelectric actuator to provide ultrasonic energy to break apart cells. The device contains pillars with varying dimensions. We hypothesize that increasing the aspect ratio of pillars will increase the efficiency of the transfer of ultrasonic energy into the fluid phase and enhance the lysing efficiency. The fluid structure ...
S. Lefeuvre, and O. Gomonova
Eurl Creawave, Toulouse, France
Siberian State Aerospace University, Krasnoyarsk, Russia
The microwave heating and processing of heterogeneous material is usually simulated using a set of coupled PDE equations in an homogeneous medium. Nowadays it is possible to describe more accurately the process with a suitable description of the heterogeneities that is at the grain level. Many authors work with spheres (circles) to represent the grains but it is difficult to achieve an ...
L. Murtomäki, and S. Kotha
University of Helsinki, Centre for Drug Research, Helsinki, Finland
Drug therapy of the posterior part of an eye is very challenging. Yet, in USA alone, there are almost 2 million people affected by age related macular degeneration. When designing a strategy for controlled-release drug delivery, it is important to take into account of physiology, absorption, distribution, metabolism, and excretion properties of a drug. Therefore, the aims of this study are: 1) to ...
A. Plana-Fattori[1,2], E. Chantoiseau[1,2], C. Doursat[1,2], and D. Flick[1,2]
AgroParisTech, Massy, France
INRA, Massy, France
Many liquid food processes involve coupled phenomena of fluid flow, heat transfer and product transformation. A typical example is the heat treatment of a starch suspension inside a tubular heat exchanger. Fluid flow influences heat transfer which determines temperature evolution along fluid trajectories. Temperature locally influences the food product transformation. The latter influences ...
V. Di Virgilio, A. Coll, S. Bermejo, and L. Castañer
Universitat Politecnica de Catalunya, Barcelona, Spain
In this work we want to explore some techniques, microfluidic and electrospray-ionization based, suitable for dynamic microarrays\' fabrication. The fabrication techniques are based on manipulation and self-assembly of selective coated micro and nanobeads. The simulation will include electro-osmotic flow, species transport, and electrostatics.
Modeling of Retinal Electrical Stimulation Using a Micro Electrode Array Coupled with the Gouy-Chapman Electrical Double Layer Model to Investigate Stimulation Efficiency
F. Dupont, R. Scapolan, C. Condemine, J.F. Bêche, M. Belleville, and P. Pham
CEA, LETI, Minatec, Grenoble, France
The electrical stimulation for retinal implant has known significant improvements in the last decades with many implantations and experimentations. The ability to create better controlled and adapted signals to increase the efficiency in stimulation is a major objective. The aim of this study is to develop a numerical platform based on COMSOL Multiphysics to simulate different waveforms. The ...
Impact of Velocity and Interfacial Tension on the Performance of Horizontal Wells in Gas Condensate Reservoirs
P. Ghahri, M. Jamiolahmady, and M. Sohrabi
Heriot Watt University, Edinburgh, United Kingdom
Drilling horizontal wells (HWs) has recently received renewed attentions with the increasing trend in exploitation of tight gas reservoirs. An accurate estimation of productivity of such systems using a numerical simulator is a challenging task, because its 3D simulation requires a fine grid exercise to capture the abrupt variation of fluid and flow parameters around the wellbore. This is ...
Institute for information and communication technologies, Bulgarian Academy of Sciences, Sofia, Bulgaria
Various haematological diseases, including leukaemia, are characterized by abnormal production of particular blood cells. Two important properties of haematopoietic stem cells (HSCs) are used in their therapy, namely: a) rapid migratory activity and ability to \'\'home\'\' to their niche in the bone marrow; b) high self-renewal and differentiation capacity, responsible for the production and ...
Z. Huijbregts, H. Schellen, and J. van Schijndel
Department of the Built Environment
Eindhoven University of Technology
Eindhoven, The Netherlands
The two wooden cabinets of Jan van Mekeren that are located in Amerongen Castle show comparable wood damage; in particular large cracks in the cabinet doors are clearly noticeable. It is assumed that these cracks were caused by bad indoor climate conditions in the castle. Combined computational modelling of the indoor climate conditions in the castle and the hygroscopic and mechanical ...
An Elastic and Hyperelastic Material Model of Joint Cartilage - Calculation of the Pressure Dependent Material Stress in Joint Cartilage
T. Reuter, and M. Hoffmann
Research Centre of Medical Technology and Biotechnology
Bad Langensalza, Germany
In this paper we introduce a elastic and hyperelastic model to describe the pressure dependent material stress in joint cartilage. We used the pressure dependent E-modulus E = f(s) to calculate the material stress. E = f(s) is a degree 4 polynomial . The indentor was pressed 0.4 mm into the tissue. The results show that the maximal stress at the contact zone between indentor and cartilage account ...