M. Miliani, F. Piccagli, C. Silvestro
Medtronic Invatec S.p.A., Roncadelle, Italy
Introduction: Chronic arterial hypertension (HTN) is a pathological condition characterized by prolonged high level of arterial blood pressure causing major damages to several human body apparata. Renal sympathetic denervation (RDN) has been found to effectively reduce systemic blood pressure. Metallic electrodes can be placed on an endovascular device connected to external radio frequency (RF) ...
J. Xi, Z. Zhang, X. Si, H. Nanda, A. Ayoola
Mechanical & Biomedical Engineering, Central Michigan University, Mt. Pleasant, MI, USA
Mechanical Engineering, California Baptist University, Riverside, CA, USA
Calvin College, Grand Rapids, MI, USA
1. It is feasible to focus and guide nanoparticles with permanent magnets and ferromagnetic particles to achieve clinically significant olfactory dosages. 2. With appropriate magnetophoretic guidance and selective drug release, an olfactory delivery efficiency of more than 20% can be achieved. 3. The optimal particle size range for magnetophoretic guidance is 10−15 µm.
O. Myers , M. Anjanappa , and C. Freidhoff 
 Mississippi State University, Mississippi State, MS, USA
 University of Maryland Baltimore County, Baltimore, MD, USA
 Northrop Grumman Corporation, Electronics Systems Sector, Baltimore, MD, USA
This paper presents a methodology towards designing, analyzing and optimizing piezoelectric interdigitated microactuators using COMSOL Multiphysics. The models used in this study were based on a circularly interdigitated design that takes advantage of primarily the d33 electromechanical piezoelectric constant coefficient. Because of the symmetric nature of the devices, 2D axisymmetric models ...
D. Scandura, G. Currenti, and C. Del Negro
Istituto Nazionale di Geofisica e Vulcanologia Sezione di Catania, Catania, Italy
In volcanic areas, the presence of heterogeneous materials and high temperatures affect the rheological behaviour of the Earth's crust that calls for considering the anelastic properties of the medium surrounding the magmatic sources. A thermo-mechanical numerical model is performed for evaluating the temperature dependency of the elasto-plastic solution. Both temperature distributions and ...
Study of Fluid and Mass Adsorption Model in the QCM-D Sensor for Characterization of Biomolecular Interaction
H.J. Kwon, C.K. Bradfield, B.T. Dodge, and G.S. Agoki
Department of Engineering and Computer Science, Andrews University, Berrien Springs, Michigan, USA
Increasing attention has been paid to application of the quartz crystal microbalance with dissipation (QCM-D) sensor for monitoring biomolecular interactions. This paper focuses on a practical application of protein-protein binding affinity measurement at low concentrations and minimal sample sizes (50-200 μl of 20-200 nM), which results in low signal measurement. A model simulating fluid ...
F. Bircher and P. Marmet
Institute of Print Technology, Bern University of Applied Sciences, Burgdorf, Switzerland
Electromagnetic micro valves are currently developed empirically or the different physics are treated separately. To accelerate the development-process and for a better understanding of the overall system, a multiphysics simulation is built up. This simulation considers the electromagnetics, the electronics (including the control of the process), the mechanics and the fluidics with respect to ...
M. V. Kisin, R. G. W. Brown, and H. S. El-Ghoroury
Ostendo Technologies, Inc., Carlsbad, CA, USA
We present a modeling software package developed at Ostendo Technologies for analysis and design of semiconductor laser and light-emitting diodes. The current database of material parameters supports complete group of III-Nitride alloys used in visible spectrum applications and can be readily extended to all III-V compounds. Self-consistent multi-band quantum-mechanical model for carrier energy ...
H. Lee, and J.V. Clark
Purdue University, West Lafayette, IN, USA
In this paper we present a method to mitigate the effect of thermally-induced noise in Micro-Electro-Mechanical Systems (MEMS) through a force feedback circuit. Inherent noise-induced vibrations, which would be inconsiderable in macro scale, are considered as a limitation in micro- and nano- scale since it diminishes the high performance of MEMS devices. For instance, depending on the stiffness ...
S. Suganthi, M. Anandraj, and L. Sujatha
Department of Electronics & Communication Engineering, Rajalakshmi Engineering College, Chennai, India
Department of Physics, Rajalakshmi Engineering College, Chennai, India
Porous Silicon (PS) can easily be formed by electrochemical etching of silicon in HF based electrolytes at room temperature. Since, PS is compatible with silicon IC technology; it finds lot of applications in the fabrication of MEMS devices. In the current study, we discuss the design of a condenser microphone using a Silicon/ Porous Silicon composite membrane as a movable plate. The performance ...
J. van Schijndel, S. Uittenbosch, and T. Thomassen
Eindhoven University of Technology
The paper presents the development of a method that determines building material and surface properties using relative simple and low-budget experiments, The method comprehends an optimal design of an experimental set up for smart determination of heat and moisture properties using both normal and inverse modeling techniques. It is concluded that the suggested methodology of the inverse ...