In questa sezione troverete i lavori presentati alle Conferenze mondiali COMSOL. Le presentazioni descrivono ricerche e prodotti innovativi progettati con COMSOL Multiphysics da colleghi di tutto il mondo. I temi delle ricerche presentate abbracciano un'ampia gamma di settori produttivi e aree applicative, in ambito elettrico, meccanico, fluidodinamico e chimico. Lo strumento di Ricerca Rapida vi permetterà di trovare le presentazioni che si riferiscono all'area di vostro interesse.

Transdermal Drug Delivery with Permeation Enhancer

A. Kermani [1], N. Elabbasi [1]
[1] Veryst Engineering, Needham, MA, USA

Transdermal drug delivery (TDD) is used to deliver drugs through the skin as an alternative to oral, intravascular, and subcutaneous routes. While there are many advantages to TDD, skin is a very effective barrier and provides resistance to drug delivery. To improve drug delivery through the skin, permeation enhancers are used. We developed an axisymmetric COMSOL Multiphysics® software model ...

Transport Phenomena and Shrinkage Modeling During Convective Drying of Vegetables

S. Curcio[1] and M. Aversa[1]
[1]Department of Engineering Modeling, University of Calabria, Arcavacata di Rende, CS, Italy

The aim of the present work is the formulation of a theoretical model describing the transport phenomena involved in food drying process. The attention has been focused on the simultaneous transfer of momentum, heat and mass occurring in a convective drier where hot dry air flows, in turbulent conditions, around the food sample. The proposed model does not rely on the specification of ...

Validation of a CFD Study of Particle Distribution in Nuclear Workplace

P. Geraldini [1],
[1] Sogin S. p. A., Rome, Italy

Understanding the air flow patterns and aerosol trajectories in ventilated rooms can provide key information for determining where to place early warning and monitoring instruments, and how to minimize hazardous materials in the worker’s breathing zone. The dispersion within rooms can be influenced by complex interactions between numerous variables, but especially ventilation design and room ...

A COMSOL Multiphysics® Study of the Temperature Effect on Chemical Permeation of Air Supply Tubes

R. Kher [1], C. Gallaschun [1], D. Crockill [1], R. Pillai [1], ,
[1] Department of Chemical Engineering, University of Pittsburgh, Pittsburgh, PA, USA

Air supply hoses are also predominantly used in the medical industry to aid in patient oxygen intake. In many situations, the outside of the hose can be contaminated with chemicals, especially if the hose lies on the ground in an environment where chemicals are easily found. Permeation and transport of chemicals into the walls of air supply hoses is a noteworthy problem in the chemical ...

Numerical Model for Predicting Heat and Mass Transfer Phenomena during Cake Baking

P. Le Bideau [1], R. Cutté [1], P. Glouannec [1], J. F. Le Page [2]
[1] Univ. Bretagne Sud, FRE CNRS 3744, IRDL, F-56100 Lorient, France
[2] DPP, ADRIA Développement, Quimper, France

A transient two-dimensional axisymmetric model is implemented in COMSOL Multiphysics® software to simulate temperatures, moisture contents distributions and cake swelling during the baking of cake contained in mold. The medium is assumed to be a deformable porous medium containing three phases: solid (dough), liquid (water) and gas. Gas phase includes two species, water and carbon dioxide. The ...

Modeling and Simulation of Drug Release through Polymer Matrices - new

V. Runkana[1], A. Pareek[1], P. Arora[2]
[1]Tata Consultancy Services, Pune, Maharashtra, India
[2]Indian Institute of Technology Delhi, New Delhi, Delhi, India

Limited drug efficacy, undesirable temporal changes in drug concentration and patient non-compliance due to frequent dosing schedule have given impetus to design of controlled drug release systems [1]. Biodegradable polymers due to their favorable and tunable properties and biocompatibility have found widespread use in the field of controlled drug delivery [2]. Exploratory in vitro experiments ...

Application of COMSOL Multiphysics® Software in Transport Phenomena Educational Processes

P. L. Mills [1], M. Vasilev [1], P. Sharma [1],
[1] Department of Chemical and Natural Gas Engineering, Texas A&M University - Kingsville, Kingsville, TX, USA

Introduction Use of simulation software for solving realistic engineering problems has grown significantly in recent years due to the availability of less expensive but more powerful computers and development of user-friendly yet robust codes. From an educational perspective, students in STEM disciplines can now solve complex problems in a relatively short period of time, which provides new ...

Miscible Viscous Fingering of Pushed Versus Pulled Interface

S. Pramanik[1], M. Mishra[1]
[1]Indian Institute of Technology Ropar, Rupnagar, Punjab, India

Viscous fingering (VF) instability has been extensively studied over past several decades in the context of various industrial, environmental and chemical processes. We try to model miscible VF at pushed or pulled interfaces using COMSOL Multiphysics®. We study the effect of the positive and negative log-mobility ratio on the fingering instability. Numerical simulation has been performed in 2D ...

Influência das Condições Ambientais Sobre a Umidade e Temperatura em Bobinas de Cartão - new

I. Neitzel[1], R. C. F. do Nascimento[1], C. C. Bueno[1]
[1]Faculdade de Telêmaco Borba - FATEB, Telêmaco Borba, Paraná, Brasil

Neste trabalho é analisado o comportamento dos perfis de temperatura e umidade e sua penetração em bobinas de papel submetidas a longos períodos de armazenagem. O modelo considera a transferência simultânea de calor e massa com o efeito Soret, mas sem o efeito Latour. O sistema é fechado em relação à umidade e aberto em relação à energia. As propriedades térmicas são dependentes da umidade e ...

Theoretical and Practical Approach for Transdermal Drug Delivery using Microneedle for Successful Skin Penetration

Jeevan J.Mahakud[1], Ziaur Reheman[2]
[1]Department of electronics and Communication engineering, Institute of technical education and research, Bhubaneswar, Odisha, India
[2]Department of electronics and instrumentation engineering, Institute of technical education and research, Bhubaneswar, Odisha, India

With the advent of MEMS, transdermal drug delivery has been developed to increase skin permeability for drug transport. Various microneedle structures have been analyzed theoretically as well as through simulation using COMSOL Multiphysics®. Then computational fluid dynamics has been presented in order to study the behavior of the fluid flow inside the microneedle cavity. In this report, the ...