K. Misiunas, N. Laohakunakorn, S. Ghosal, O. Otto, U. F. Keyser
University of Cambridge, Cambridge, UK
Northwestern University, Evanston, IL, USA
The motion of DNA in crowded environments is a common theme in physics and biology. Examples include gel electrophoresis and the self-interaction of DNA within cells and viral capsids. Here we study the interaction of multiple DNA molecules within a nanopore by tethering the DNA to a bead held in a laser optical trap to produce a "molecular tug-of-war". We measure this tether force as a function ...
Computational Micro Fluid Dynamics: Part 2: Case Study: Flow Patterning by Phase-shifted Electroosmotic Flows
Institut für Mikrotechnik Mainz, Fluidik und Simulation, Mainz
In the second part of the presentation, we focus on the simulation of electroosmotic flows (EOF). Here we present a new method of generating complex flow patterns relying on the use of EOF in combination with specially designed delay loops. The plug retardation in the delay loop is described in terms of a basic network model and a detailed FEM model (COMSOL Multiphysics). Simulation ...
Study of Fluid and Mass Adsorption Model in the QCM-D Sensor for Characterization of Biomolecular Interaction
H.J. Kwon, C.K. Bradfield, B.T. Dodge, and G.S. Agoki
Department of Engineering and Computer Science, Andrews University, Berrien Springs, Michigan, USA
Increasing attention has been paid to application of the quartz crystal microbalance with dissipation (QCM-D) sensor for monitoring biomolecular interactions. This paper focuses on a practical application of protein-protein binding affinity measurement at low concentrations and minimal sample sizes (50-200 μl of 20-200 nM), which results in low signal measurement. A model simulating fluid ...
In this presentation we outline our recent work on Magnetic Liquids, and the great number of application areas these are used. Ferrofluids are nanometer sized magnetic particles, covered by a surfactant, suspended in a carrier medium compatible with the surfactant material. Ferrofluids are applicable to a great and ever increasing number of application areas, such as: • Liquid Seals and ...
H-Y. Shen, H-P. Tsui, J-C .Hung, S-Y. Lin, and B-H. Yan
Metal Industries Research and Development Centre, Taichung, Taiwan
National Central University, Chungli, Taiwan
In this work, the process of micro-channels in electrochemical micro-milling by using rotating magnet assisted helical tool is presented. The results show helical tool and Lorentz force of the rotating magnetic field that enhance the renewal of the electrolyte and machining efficiency. The feed rate can be raised under the magnetic field assisted in terms of experimental results; moreover, the ...
University of Applied Sciences, Regensburg, Germany
This paper gives an overview of modelling microsensors on geometry and system level. The focus will be on the generation of the multiphysics reduced order system model and the coupling with package and ASIC models. The method is based on modal superposition. This means all the details of the sensor can be considered in a finite element model. The mechanical mode shapes of this model form the ...
Design and Development of Microsystems within a Corporate Research Environment by Utilizing Comsol Multiphysics
Corporate Research & Technologies
Alexander Frey received his M.A. degree from the University of Texas, Austin, in 1994, the Dipl. Phys. degree from the University of Wuerzburg, Germany in 1997 and the PhD from the Saarland University, Germany in 2010. In 1997 he joined Research Laboratories of Siemens working on the design of DRAM sensing circuits. In 1999 he joined Corporate Research, Infineon, Munich, Germany. He was engaged ...
Kinetic Investigation of a Mechanism for Generating Microstructures on Polycrystalline Substrates Using an Electroplating Process
T. Soares, H. Mozaffari, H. Reinecke
Universität Freiburg, Freiburg im Breisgau, BW, Germany
Hochschule Furtwangen, Tuttlingen, BW, Germany
The purpose of this study is to understand the growth mechanism of copper (Cu) films on a Cu-Zn system substrate with a pre-defined pattern. The pattern was defined by conducting a selective etching process on a two-phase polycrystalline substrate. As a result of this process, there were etched regions correspondent to beta-phase crystals and quasi non-etched regions that belong to alpha-phase ...
AC Electrothermal Characterization of Doped-Si Heated Microcantilevers Using Frequency-Domain Finite Element Analysis
K. Park, S. Hamian, A. M. Gauffreau, T. Walsh
Mechanical Engineering Department, University of Utah, Salt Lake City, UT, USA
Department of Mechanical, Industrial & Systems Engineering, University of Rhode Island, Kingston, RI, USA
This work investigates the frequency-dependent electrothermal behaviors of freestanding doped-silicon heated microcantilever probes operating under the periodic (ac) Joule heating. The transient heat conduction equation for each component (i.e., the low-doped heater region, the high-doped constriction region, and the high-doped leg region) is solved using the general heat transfer module for DC ...
T. H. Hanley, H. T. D. Grigg, B. J. Gallacher
Newcastle University, Newcastle-Upon-Tyne, UK
Introducing a disorder into a finite periodic oscillatory system induces the presence of a 'trapped mode': a mode in which the displacement field is localised to the region of the disorder. A main inhibitor to MEMS resonators achieving a high quality (Q) factor is energy radiation through the support to the substrate. The trapped modes present a way to tune this to a minimal value. An initial ...