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In questa sezione troverete i lavori presentati alle Conferenze mondiali COMSOL. Le presentazioni descrivono ricerche e prodotti innovativi progettati con COMSOL Multiphysics da colleghi di tutto il mondo. I temi delle ricerche presentate abbracciano un'ampia gamma di settori produttivi e aree applicative, in ambito elettrico, meccanico, fluidodinamico e chimico. Lo strumento di Ricerca Rapida vi permetterà di trovare le presentazioni che si riferiscono all'area di vostro interesse.

Heat Transfer and Phase Transformation on Matrix Assisted Pulsed Laser Evaporation (MAPLE) of Biocompatible Thin Layers

E. Lacatus[1], G.C. Alecu[1], M.A. Sopronyi[2], A. Tudor[1]
[1]POLITEHNICA University of Bucharest, Bucharest, Romania
[2]INFLPR -National Institute for Laser Plasma and Radiation Physics, Bucharest, Romania

Matrix Assisted Pulsed Laser Evaporation (MAPLE) technique is used for the deposition of high quality biocompatible polymer thin films. During the deposition process the temperature of the laser target should be kept below 193K to assure the proper quality of both evaporation and deposition phases of the process. On a first approach COMSOL Multiphysics® was used to describe and analyze the ...

Acoustic Field Comparison of High Intensity Focused Ultrasound Using Experimental Characterization and Finite Element Simulation

J. L. Teja[1], A. Vera[1], L. Leija[1]
[1]Department of Electrical Engineering, Cinvestav-IPN, Mexico D.F., Mexico

High Intensity Focused Ultrasound (HIFU) is used as a noninvasive technique of tissue heating and ablation for different medical treatments. This paper presents a quantitative comparison of HIFU acoustic fields experimentally obtained versus simulated acoustic fields. Acoustic field characterization was realized in two HIFU transducers using water as a propagation medium. Also, simulations were ...

Rapid Prototyping of Biosensing Surface Plasmon Resonance Devices using COMSOL & Matlab software

J.J. Dubowski[1], and D.Carrier[1]
[1]Department of Electrical and Computer Engineering, Université de Sherbrooke, Quebec, Canada

We present a Finite Element Method simulation procedure that allows rapid development of prototype devices comprising novel self-referenced interference SPR (surface plasmon resonance) biosensing microstructures. The procedure takes advantage of  COMSOL Multiphysics and MATLAB software and their bi-directional link. The simulation is made using COMSOL RF Module, 2D harmonic propagation ...

Model of an Interdigitated Electrodes System for Cell Counting Based on Impedance Spectroscopy

E. Bianchi[1][2], F. Bellati[1], E. Rollo[2], G. Dubini[1], C. Guiducci[2]
[1]Politecnico di Milano, LaBS, Laboratory of Biological Structure Mechanics, Milano, Italy
[2]Swiss Federal Institute of Technology (EPFL), Laboratory of Life Sciences Electronics - Swiss Up Chair, Lausanne, Switzerland

A model of a cell counter sensor based on Impedance Spectroscopy (IS) has been implemented in COMSOL Multiphysics. The cell counter is a silicon-based microdevice consisting in 3D electrodes placed in a wide microchannel: cells flow in the microchannel through the electrodes to be detected. The model allows to evaluate the functionality of the device depending on geometrical parameters and ...

Analysis of 3D Biocompatible Additive Structure Using COMSOL Multiphysics® Software - new

E. Lacatus[1], M. A. Sopronyi[2], G. C. Alecu[1], A. Tudor[1]
[1]Polytechnic University of Bucharest, Bucharest, Romania
[2]INFLPR -National Institute for Laser Plasma and Radiation Physics, Bucharest, Romania

For biocompatible prosthetics, from dental implants up to bone parts, manufacturers have to find the best way to correlate process parameters and the material properties as to meet the unique needs of individuals. Additive manufacturing techniques aim at creating complex biocompatible structures able to overcome the present shortfalls of the metal and metal alloys implants related to ...

Simulation of Chemotractant Gradients in Microfluidic Channels to Study Cell Migration Mechanism in Silico

P. Wallin[1], E. Bernson[1], J. Gold[1]
[1]Chalmers University of Technology, Applied Physics, Biological Physics, Gothenburg, Sweden

Cell migration of endothelial cells along gradients is an important process in vivo and an interesting target for cancer therapeutics. Microfluidics offer very powerful tools to study such migration processes in detail in the lab. In this study, we describe a model to simulate molecular gradients in a diffusion based microfluidic gradient generator and how a cell senses these gradients via cell ...

Simulation Organogenesis in COMSOL: Deforming and Interacting Domains

D. Iber[1], D. Menshykau[1]
[1]D-BSSE, ETH Zurich, Basel, Switzerland

Organogenesis is a tightly regulated process that has been studied experimentally for decades. We are developing mechanistic models for the morphogenesis of limbs, lungs, and kidneys with a view to integrate available knowledge and to better understand the underlying regulatory logic. Organ size changes dramatically during development, and tissues are composed of several layers that may expand ...

Calibration of a Bio-Kinetic Model to Simulate Microalgae Growth - new

A. Solimeno[1], J. Garcia[2]
[1]Department of Hydraulic, Maritime and Environmental Engineering, Universitat Politècnica de Catalunya, Barcelona, Spain
[2]Universitat Politecnica de Catalunya, Barcelona, Spain

The aim of present work is to present and calibrate a new mechanistic model that includes physical and biokinetic processes to reproduce the algae growth in photobioreactor or ponds during long-term scenarios. A COMSOL Multiphysics® model is used to implement the microalgae processes mainly based on River Water Quality Model 1 (RWQM1) (Reichert et al., 2011). The main innovation of the model is ...

Modeling Drug Release from Materials Based on Electrospun Nanofibers

P. Nakielski[1], T. Kowalczyk[1], T.A. Kowalewski[1]
[1]Institute of Fundamental Technological Research Polish Academy of Sciences, Warsaw, Poland

Comprehensive studies of drug transport in nanofibres based mats have been performed to predict drug release kinetics. The paper presents our approach to analyze the impact of fibers arrangement, one of the parameters varied in our parallel experimental studies. COMSOL Multiphysics® has been used to assess the impact of the various purposed arrangements of fibers within the mat. Drug release ...

Stochastic Diffusion of Calcium Ions Through a Nanopore in the Cell Membrane Created by Electroporation - new

O. Henao[1], V. Gómez[1], I. De La Pava[1], J. Sánchez [1]
[1]Grupo Fisiología Celular y Aplicada, Universidad Tecnológica de Pereira, Pereira, Risaralda, Colombia

We simulated the diffusion of calcium ions through a nanopore created in the cell membrane by electroporation, in presence and absence of the external electric field responsible of the membrane permeabilization. First we solved the set of coupled differential equations that describe the process of ionic diffusion in a 2D nanopore model using the AC/DC Module and the Transport of Diluted Species ...