Uncertainty Quantification of Focused Ultrasound Induced Heating with FDA Tissue Mimicking Material

Application ID: 148581


This model analyzes the uncertainty in focused ultrasound induced tissue heating. The material properties for the tissue mimicking material, including the uncertainty, are taken from the FDA Medical Device Development Tool: Tissue Mimicking Material (TMM) for Preclinical Acoustic Performance Characterization of High Intensity Therapeutic Ultrasound (HITU) Devices. The model includes Acoustics and Bioheat Transfer physics and predicts uncertainty in peak temperature of about 0.1 degrees during the ultrasonic heating process for the input parameter set modeled.

This model example illustrates applications of this type that would nominally be built using the following products: