Harvey Buck, Roche Diagnostics Operations, Inc., Indianapolis, IN, USA
The test strips in glucose monitors, widely used by people with diabetes to maintain good health, are sensitive to chemical interferences and environmental conditions. The manufacturing process and electrode configuration of these strips also affects response accuracy. Researchers at Roche Diagnostics Operations, Inc. used multiphysics simulation to analyze the chemical reactions and voltage response in their glucometers.
Using COMSOL Multiphysics, Harvey Buck, principal scientist at Roche, investigated different configurations and materials used in the test strips. He analyzed the electrical response to an applied voltage during the chemical reaction catalyzed in a sample. Through numerical simulation, he predicted the sensitivity of electrical impedance measurements to mechanical properties of the sensor. He also optimized the electrode configuration, maximized sensitivity to cell fraction in a sample, and minimized sensitivity to manufacturing tolerances. These simulation results have given the Roche team a better understanding of their integrated sensor design for glucose monitoring.
Suggested Stories
Boost Sales and Build Stronger Relationships with the Deployment of Simulation Apps
Proofs of concept are often the deciding factor in gaining the trust of a customer and generating a sale. But for high ...
How Fast Do Elevated Temperatures Reach the Cell Interior?
Lithium-ion batteries, which have a tendency to degrade at high temperatures, must adhere to stringent regulations ...
Elevating the Performance of Ionization Gauges with Simulation
Semiconductor manufacturing and particle physics research depend on high-vacuum or ultra-high-vacuum (HV/UHV) ...
Magnets Improve Quality of High-Power Laser Beam Welding
High-power laser beam welding uses a localized heat source to achieve narrow deep welds and high welding rates. ...
