Presentazioni e Articoli Tecnici

In questa sezione troverete i lavori presentati alle Conferenze mondiali COMSOL. Le presentazioni descrivono ricerche e prodotti innovativi progettati con COMSOL Multiphysics da colleghi di tutto il mondo. I temi delle ricerche presentate abbracciano un'ampia gamma di settori produttivi e aree applicative, in ambito elettrico, meccanico, fluidodinamico e chimico. Lo strumento di Ricerca Rapida vi permetterà di trovare le presentazioni che si riferiscono all'area di vostro interesse.

Predicting the Mechanical Properties of Biological Inspired Diatoms

M.F.D. Moreno, L.P. Davila, and F. Viscarra
University of California at Merced, Merced, CA, USA

Our computational work has focused on calculating the mechanical properties of diatom silica structures using COMSOL Multiphysics. We have used selected diatom geometries based on their structure classification and different loading conditions. Various 3D structures were modeled on Pro/ENGINEER, and then exported to COMSOL for further analysis. The mechanical behavior of diatom structures was ...

Reducing Mitigating Factors That Lead to Clotting of the Arteries From Prolonged Hemodialysis

K. Hegde[1], J. Clark[1], A.G. Akingba[2], and J.V. Clark[1]
[1]Purdue University, West Lafayette, IN, USA,
[2]Indiana University, Indianapolis, IN, USA

In this paper we present a computational study of our novel arteriovenous (AV)-shunt interface device that is expected to reduce the mitigating factors that lead to clotting of the AV-shunts from prolonged hemodialysis. Kidney failure affects about 300,000 (about 0.1%) of the United States population. About 20% of the hemodialysis hospitalizations in the U.S. are due to clotting-related vascular ...

Patient-specific Modelling of Blood-flow in Cerebral Aneurysms

D. Zajarias-Fainsod[1], M.J. Chappell[1], J.F. Collingwood[1], A. Rennie[2], S. Nagaraja[2], and A. Wilson[2]
[1]University of Warwick, Coventry, UK,
[2]University Hospital Coventry and Warwickshire NHS Trust, Coventry, UK

A first stage in this research was to determine the feasibility of patient-specific modelling and the use of in-silico techniques to study flow for the first time in the same vessels with and without an aneurysm. Three-dimensional renderings of the cerebral blood vessels were reconstructed from computed tomography angiograms of the head using MATLAB (The MathWorks) for image processing and ...

Design of Multiple Ground System for Maternal Defibrillation - new

A. Jeremic[1], E. Khoshrowshahli[2]
[1]Electrical & Computer Engineering, McMaster University, Hamilton, ON, Canada
[2]Biomedical Engineering, McMaster University, Hamilton, ON, Canada

Although cardiac arrest may be statistically insignificant event financial and more important emotional costs in such cases are quite devastating. In this paper we study the effects of multiple grounding pads. Namely, we believe that by placing multiple pads in the lower abdominal part we would be able to decrease the current density that would be dissipated to fetus and amniotic liquid. ...

Microwave Exposure System for In Vitro and In Vivo Studies - new

C. Nadovich[1, 2], W. D. Jemison[2], J. A. Stoute[3], C. Spadafora[4]
[1]Lafayette College, Easton, PA, USA
[2]Clarkson University, Potsdam, NY, USA
[3]Pennsylvania State University, Hershey, PA, USA
[4]INDICASAT AIP, Ciudad del Saber, Panama

A computer controlled microwave exposure system and specialized applicators were constructed for the purpose of facilitating accurate observations of microwave radiation effects on uninfected and infected biological tissue in vitro and in vivo under different electromagnetic modalities and exposure configuration. To address diverse requirements, three different applicators were developed: a ...

Stochastic Diffusion of Calcium Ions Through a Nanopore in the Cell Membrane Created by Electroporation - new

O. Henao[1], V. Gómez[1], I. De La Pava[1], J. Sánchez [1]
[1]Grupo Fisiología Celular y Aplicada, Universidad Tecnológica de Pereira, Pereira, Risaralda, Colombia

We simulated the diffusion of calcium ions through a nanopore created in the cell membrane by electroporation, in presence and absence of the external electric field responsible of the membrane permeabilization. First we solved the set of coupled differential equations that describe the process of ionic diffusion in a 2D nanopore model using the AC/DC Module and the Transport of Diluted Species ...

Simulation of Normal and Cancerous T-cell Membrane Electroporation - new

O. Henao[1], V. Gómez[1], I. De la Pava[1], J. Sánchez[1]
[1]Grupo Fisiología Celular y Aplicada, Universidad Tecnológica de Pereira, Pereira, Risaralda, Colombia

Electroporation is an increase of the cell membrane permeability due to the formation of aqueous pores in it when the cell is under the influence of an intense electric field [1][2]. The formation of such pores in the membrane can be used to enhance the uptake of chemotherapeutic drugs into the cell in a cancer treatment known as electrochemotherapy [3]. In some cases the direct experimental ...

Solving Calcium Spatiotemporal Diffusion Using COMSOL Multiphysics® Software - new

L. Garber[1,2], G. S. B. Williams[2], W. J. Lederer[2]
[1]Fischell Department of Bioengineering, University of Maryland, Baltimore, MD, USA
[2]Center for Biomedical Engineering & Technology, University of Maryland, Baltimore, MD, USA

This project involves a simplified biological problem that was used to test the potential of COMSOL Multiphysics® software for cardiac myocyte spatial modeling. We made several assumptions to simplify the biological complexity and to highlight the geometrical structures (i.e., lack of sarcoplasmic reticulum, lack of contractile apparatus). We explored the role of the t-tubular network on ...

Analysis of Heat Transfer in a Complex Three Dimensional Structure Fabricated by Additive Manufacturing - new

C. Settle[1], K. Hoshino[1]
[1]Biomedical Engineering Department, University of Connecticut, Storrs, CT, USA

The goal of this study was to create a three dimensionally designed biomedical device with multiple functionalities and analyze its simulated heat transfer. The device would be fabricated through additive manufacturing; specifically electron beam melting (EBM). EBM has a feature size constraint of 1 mm (acceptable for this design) and is only capable of manufacturing titanium alloys [2]; a ...

Biofluid-Structural Interaction in Abdominal Aortic Aneurysm for Predicting Timeline to Rupture: The Effect of Hypertension and Aorta Wall Material Properties - new

K. Cluff[1], H. Mehraein[1], G. Jayakumar[2]
[1]Bioengineering, Wichita State University, Wichita, KS, USA
[2]Industrial & Manufacturing Engineering, Wichita State University, Wichita, KS, USA

An abdominal aortic aneurysm (AAA) is a bulge formed in the large blood vessels that supply blood to the abdomen, pelvis, and legs. A fluid structure interaction model was developed in a 3D aortic aneurysm model, which was constructed from abdominal CT scan images. Combining medical imaging and computational fluid dynamics (CFD) in a time dependent study allowed the determination of wall ...

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